AOCCN2017

講演情報

Poster Presentation

[P2-136~192] Poster Presentation 2

2017年5月12日(金) 10:00 〜 15:40 Poster Room B (1F Argos F)

[P2-140] Neurological Outcomes Of Spontaneous Superficial Parenchymal And Leptomeningeal Hemorrhage

Yoshitaka Mizobe (Division of Neurology, Kanagawa Children's Medical Center, Kanagawa, Japan)

[Introduction] Spontaneous Superficial Parenchymal and Leptomeningeal Hemorrhage (SSPLH) is rare in full-term neonates without obvious underlying diseases. In this study, we evaluated the long-term neurological outcomes of seven SSPLH patients. [Methodology] We evaluated prenatal histories, labor and delivery histories, clinical presentations, imaging studies, management, and outcomes of seven newborns with SSPLH from 2008 to 2015 retrospectively. Clinical follow-up was done in five patients using the Kyoto Scale of Psychological Development (KSPD) and the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV). [Results] All neonates were delivered vaginally (one with vacuum assistance) and high 5-minute APGAR scores. Within the first three days of life, most presented with apnea or seizures or dystithia. Neuroimaging subsequently revealed superficial parenchymal and leptomeningeal hemorrhage except for cerebellar vermis. Four occurred in the frontal lobe under the squamosal suture and two occurred in the lateral temporal lobe adjacent to the pterion. The mean follow-up period was 3.6 years (range, 1.5-8 years). KSPD was performed on four patients at 18 months and WISC-IV was performed on one at 6 years old by trained psychologists. The median overall DQ of KSPD was 101 and the FSIQ of WISC-IV was 87. One patient had complex febrile seizures but all patients were neurologically normal during the follow-up period. [Conclusions] We suggested that the neurological outcomes of SSPLH was good during the follow-up period. In future, the study of furthermore long-term neurological outcomes should be designed.