[AsCNP_S16] シンポジウム16
Stresses and psychiatric diseases ~ mechanisms, gender, treatment ~

2019年10月11日(金) 10:30 〜 12:10 第16会場 (平安)

Organizer / Chair: ‌Atsumi NITTA (Dept of Pharmaceutical Thera & Neuropharmacol, Fac of Pharmaceutical Sci. Grad Sch of Med and Pharm Sci.University of Toyama, Toyama, Japan), Co-chair: Hiroshi ICHINOSE (School of Life Science and Technology, Tokyo Institute of Technology, Japan), Discussants: ‌Kazuto KOBAYASHI (Department of Molecular Genetics, Fukushima Medical University, Japan), Kiyoyuki KITAICHI (Department of Biomedical Pharmaceutics, Gifu Pharmaceutical University, Japan)

We are always receiving many and various stresses. Stresses sometime induce depressive disorder and anxiety, fall to drug addiction. Many patients are not received efficient therapy, since mechanism of onset of depressive disorders anxiety is not completely clarified, especially induced by stresses. Further many factors could be involved for the onset depressive disorders and/or anxiety, cocaine or methamphetamine, abuse, neglect, gene, environment, trauma, gender and etc. However we do not perfect medical tools for the depression and/or anxiety.
Here, we will focus to gender differences in the depression, GluK3-containing kainate, genomic factor of Shati/Nat8L.
We would like to discuss the mechanism of depression and anxiety, in order to novel medical tools in near future.

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10:30 〜 10:33

[AsCNP-S16-Introduction] Introduction

^○Atsumi NITTA (Dept of Pharmaceutical Thera & Neuropharmacol, Fac of Pharmaceutical Sci. Grad Sch of Med and Pharm Sci.University of Toyama, Toyama, Japan)

10:33 〜 11:08

[AsCNP-S16-1] GluK3-containing kainate receptors influence the anxiolytic-like activities in mice

^○Miho TERUNUMA¹, Izumi IIDA¹, Masahiko WATANABE², Kenji SAKIMURA³ (1. Division of Oral Biochemistry, Niigata University, Niigata, Japan, 2. Department of Anatomy, Hokkaido University School of Medicine, Japan, 3. Department of Animal Model Development, Brain Research Institute, Niigata University, Japan )

11:08 〜 11:43

[AsCNP-S16-2] Sex difference in the glutamate-glutamine transfer in animal model of depression

^○Akiko SHIMAMOTO¹, Virginie RAPPENEAU¹, Havisha MUNJAL¹, Tonie FARRIS¹, Cindy MOORE³, Charles K MESHUL^{2, 3} (1. Department of Neuroscience and Pharmacology, Meharry Medical College, USA, 2. Department of Behavioral Neuroscience, Oregon Health and Science University, USA, 3. Veterans Affairs Portland, USA)

11:43 〜 12:10

[AsCNP-S16-3] Overexpression of striatal Shati/Nat8l induces vulnerability to depressive behavior

^○Atsumi NITTA¹, Miyanishi HAJIME¹, Kyosuke UNO² (1. Dept of Pharmaceutical Thera & Neuropharmacol, Fac of Pharmaceutical Sci. Grad Sch of Med and Pharm Sci.University of Toyama, Toyama, Japan, 2. Laboratory of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, Japan)