Asuri N. Prasad^1,3,4，Prashanth Rajasekar²，Victoria M. Siu^3,4,6，C. Anthony Rupar^3,4,5,6，Chitra Prasad^3,4,5,6. (1. Division of Pediatric Neurology，2. Queens University School of Medicine, Kingston, ON, Canada，3. Division of Medical Genetics，4. Department of Pediatrics，5. Departments of Pathology and Laboratory Medicine and Biochemistry, Faculty of Medicine, Western University and London Health Sciences Centre, London, ON, Canada.，6. Children's Health Research Institute, London, ON, Canada)