The 35th CINP World Congress of Neuropsychopharmacology

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[CINP2024] Poster Session

CINP2024 » Poster Session

Epilepsy

2024年5月24日(金) 17:30 〜 18:30 CINP Poster Session Hall (Lobby Gallery)

[P128] Development of a physiologically-based pharmacokinetic (PBPK) model to predict plasma and brain exposure following administration of valproic acid and clobazam in combination treatment regimen for Dravet syndrome in children

*Nattapon Jaisupa1, Michael Ashton1, Sofia Birgersson1 (1. Unit for Pharmacokinetic and Drug Metabolism, Department of Pharmacology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden)

キーワード:valproic acid, clobazam, physiologically-base pharmacokinetic model

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