Preclinical - Others (1)

[P342] Loss of Akain1, an endogenous microprotein that inhibits PKA localization, attenuates contextual discrimination and behavioral flexibility in mice

Kazuki Fujii^1,2,3, Yumie Koshidaka², Mayumi Adachi², Yuko Yanagibashi², Mina Matsuo², Shoko Hongo², Hirofumi Nishizono⁴, Ichiro Takasaki⁵, Nobuyuki Kurosawa^6,7, Yasunori Aizawa^8,9, *Keizo Takao^1,2,3,7 (1. Department of Behavioral Physiology, Faculty of Medicine, University of Toyama, Toyama, Japan, 2. Life Science Research Center, University of Toyama, Toyama, Japan, 3. Research Center for Idling Brain Science, University of Toyama, Toyama, Japan, 4. Medical Research Institute, Kanazawa Medical University, Ishikawa, Japan, 5. Department of Pharmacology, Graduate School of Science and Engineering, University of Toyama, Toyama, Japan, 6. Laboratory of Molecular and Cellular Biology, Department of Life Sciences and Bioengineering, Faculty of Engineering, University of Toyama, Toyama, Japan, 7. Center for Advanced Antibody Drug Development, University of Toyama, Toyama, Japan, 8. Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan, 9. Kanagawa Institute of Industrial Science and Technology, Ebina, Japan)

キーワード：microprotein, PKA, behavioral flexibility