Preclinical - Others (1)

[P344] KNT-127, a delta opioid receptor agonist, ameliorates psychological stress-induced irritable bowel syndrome-like symptoms through the central nervous system

*Toshinori Yoshioka¹, Daisuke Yamada¹, Mayuna Yamazaki¹, Takumi Hamano¹, Sayaka Kimiki¹, Hiroshi Nagase², Akiyoshi Saitoh¹ (1. Laboratory of Pharmacology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan, 2. University of Tsukuba, Ibaraki, Japan)

キーワード：psychological stress, gut–brain axis, irritable bowel syndrome, delta opioid receptor, insular cortex