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[P361] Glia responses are associated with abnormal behaviors in an animal model of tau pathologies

*Yue Liu¹, Hiroyuki Mizoguchi^1,2, Akira Sobue³, Naruhiko Sahara⁴, Koji Yamanaka³, Kiyofumi Yamada¹ (1. Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Nagoya, Japan, 2. Medical Interactive Research and Academia-Industry Collaboration Center, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan, 3. Department of Neuroscience & Pathobiology, Research Institute of Environmental Medicine, Nagoya University, Nagoya, Japan, 4. Department of Functional Brain Imaging, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan)

Keywords:Alzheimer’s disease, Dementia, Tau, neuroinflammation