Short Communications 4
Preclinical - Others

[SC4-3] The Effect of α6 Subunit-Containing GABA_A Receptor Positive Allosteric Modulators on Striatal Slitrk1-knockdown Mice, A Novel Animal Model for Tourette Syndrome.

*Jung Chieh Du^1,4, Man Hsin Chang¹, Chen Jiun Yeh¹, Ming Tatt Lee^1,6,7, Hsin Jung Lee², Shu Hui Chuang², Lih Chu Chiou^1,2,3,5 (1. Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, 2. Department of Pharmacology, College of Medicine, National Taiwan University, Taipei, Taiwan, 3. Graduate Institute of Brain and Mind Sciences, College of Medicine, National Taiwan University, Taipei, Taiwan, 4. Department of Pediatrics, Taipei City Hospital, Zhongxiao Branch, Taipei, Taiwan, 5. Graduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan, 6. Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia, 7. Centre of Research for Mental Health and Wellbeing, UCSI University, Kuala Lumpur , Malaysia)

Keywords:Preclinical, Slitrk1, Tourette syndrome, Striatum, Cholinergic interneuron