In vivo phenotyping for CYP3A by a single-point determination of plasma concentration ratio of endogenous 6&beta;-hydroxycortisol to cortisol

Ryohei Hirano

[P27-10-6] In vivo phenotyping for CYP3A by a single-point determination of plasma concentration ratio of endogenous 6β-hydroxycortisol to cortisol

Ryohei Hirano¹, Hiromi Shibasaki-Hirano², Akitomo Yokokawa³, Takashi Furuta⁴ (1.Tokyo University of Pharmacy and Life Sciences, 2.Tokyo University of Pharmacy and Life Sciences, 3.Tokyo University of Pharmacy and Life Sciences, 4.Tokyo University of Pharmacy and Life Sciences)

キーワード：CYP3A, biomarker, 6β-hydroxycortisol, phenotyping, LC-MS/MS

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講演情報

[P27-10] P27-10: Pharmacokinetics and pharmacogenetics

[P27-10-6] In vivo phenotyping for CYP3A by a single-point determination of plasma concentration ratio of endogenous 6β-hydroxycortisol to cortisol

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