Novel Strategy of Enhancement of RNase H Mediated Target RNA Digestion Activities by DNA-Artificial Nucleic Acid Chimera with Site Selective Cleavage Toward Application of COVID-19 Therapeutics

Takehiko Wada

[P-13] Novel Strategy of Enhancement of RNase H Mediated Target RNA Digestion Activities by DNA-Artificial Nucleic Acid Chimera with Site Selective Cleavage Toward Application of COVID-19 Therapeutics

*Takehiko Wada¹, Nozomu Ishiwata¹, Kazutoshi Fujita¹, Masahito Inagaki,^2,1, Hironori Hayashi³, Yuto Horiuchi¹, Yuki Igarashi¹, Kosuke Machida¹, Masaru Morikawa¹, Masaki Nishijima¹, Yasuyuki Araki¹, Eiichi Kodama³ (1. IMRAM, Tohoku University, 2. Graduate School of Science, Nagoya Univeersity, 3. IRDeS, Tohoku University)

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Poster(17:30-19:30)

[P-13] Novel Strategy of Enhancement of RNase H Mediated Target RNA Digestion Activities by DNA-Artificial Nucleic Acid Chimera with Site Selective Cleavage Toward Application of COVID-19 Therapeutics

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