[13p-B1-1~13] ナノバイオテクノロジーとバイオセンシングに関するジョイントシンポジウム

▲ [13p-B1-11] A Nanobiosensor Based on Structural Analysis of Nanobiomaterials in Solutions

〇Sou Ryuzaki¹、Makusu Tsutsui²、Takao Yasui³、Kazumichi Yokota²、Kaoru Tamada¹、Yoshinobu Baba³、Masateru Taniguchi² (1.Kyushu Univ.、2.Osaka Univ.、3.Nagoya Univ.)

キーワード：nanopore

Rapid structural analysis methods for biomolecules and biomaterials consisting of single or several molecules in solution represent innovative technologies to reveal their functions because the functions strongly depend on their own structures. Here we report the development of low-aspect-ratio nanopores with a spatial resolution of ca.35.5 nm. Combining the present state-of-the-art technologies with multiphysics simulation methods to translate ionic current data into structures of nanomaterials passing through a nanopore, we have achieved rapid structural analysis of single gold nanorods, single polystyrene (Pst) beads, and single dumbbell-like Pst beads in aqueous solutions.