Tadao Nagasaki^1,2, Jinming Zhao², Yanhan Deng², John B Trudeau², Yoshinori Minami², Sally E Wenzel² (1.Department of Respiratory Medicine, Osaka Saiseikai Nakatsu Hospital, Japan, 2.Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, USA)

Kaori Kawakami¹, Tomomitsu Miyasaka¹, Yutaka Nakamura², Satoshi Miyata³, Miki Sato¹, Ichiro Sora⁴, Hirohito Metoki⁵, Kohei Yamauchi⁶, Julie A Blendy⁷, Tasuku Kawano¹, Hiroaki Shimokawa^3,8, Tomoko Takahashi¹, Motoaki Takayanagi¹, Isao Ohno² (1.Division of Pathophysiology, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Japan, 2.Center for Medical Education, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan, 3.Department of Evidence-Based Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan, 4.Department of Psychiatry, Kobe University Graduate School of Medicine, Japan, 5.Division of Public Health, Hygiene and Epidemiology Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Japan, 6.Division of Respirology, Department of Internal Medicine, Takizawa Central Hospital, Japan, 7.Department of Pharmacology, University of Pennsylvania Medical School, USA, 8.Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan)

Toshiaki Shimizu^1,2, Kazuyuki Nakagome¹, Yury A Bochkov³, Yutaka Ueda¹, Takehito Kobayashi¹, Tomoyuki Soma¹, Hiroaki Harada², Keishi Fujio², James E Gern^3,4, Makoto Nagata¹ (1.Department of Respiratory Medicine and Allergy Center, Saitama Medical University, Japan, 2.Department of Allergy and Rheumatology, Graduate School of Medicine, University of Tokyo, Japan, 3.Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin, USA, 4.Department of Medicine, School of Medicine and Public Health, University of Wisconsin, USA)

Hiroaki Tsurumaki¹, Haruka Aoki-Saito¹, Yasuhiko Koga¹, Makiko Sato¹, Masakiyo Yatomi¹, Asuka Jingu¹, Kenichiro Hara¹, Noriaki Sunaga¹, Seishi Yoshimi², Toshitaka Maeno¹, Takeshi Hisada³ (1.Department of Respiratory Medicine, Gunma University Graduate School of Medicine, Japan, 2.Tone Central Hospital, Japan, 3.Gunma University, Faculty of Medicine School of Health Sciences, Japan)

Takahiro Matsuyama, Kentaro Machida, Yoichi Doutake, Koichi Takagi, Hiromasa Inoue (Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, Japan)

Yuki Hoshino^1,2, Tomoyuki Soma^1,2, Yoshitaka Uchida^1,2, Sachiko Miyauchi^1,2, Hidetoshi Iemura^1,2, Erika Naito^1,2, Kazuki Katayama^1,2, Ryu Sekiya^1,2, Kazuyuki Nakagome^1,2, Makoto Nagata^1,2 (1.Department of Respiratory Medicine, Saitama Medical University, Japan, 2.Allergy Center, Saitama Medical University, Japan)

Luna Okubo¹, Naoya Takeda², Yoshihiro Suzuki², Kuniya Nakashima², Motoyo Asano², Fumika Koike¹, Akane Ide¹, Miho Akaza¹, Yasunari Miyazaki³, Yuki Sumi¹ (1.Department of Respiratory and Nervous System Science, Tokyo Medical and Dental University, Japan, 2.Department of Respiratory Medicine and Allergy, Kariya Toyota General Hospital, Japan, 3.Department of Respiratory Medicine, Tokyo Medical and Dental Univercity, Japan)

Toshiyuki Koya¹, Akira Saito¹, Natsumi Sakai¹, Mio Toyama¹, Keisuke Tsukioka¹, Yosuke Kimura¹, Masachika Hayashi¹, Takashi Hasegawa², Toshiaki Kikuchi¹ (1.Department of Respiratory Medicine and Infectious Diseases, Niigata University Graduate School of Medical and Dental Sciences, Japan, 2.Department of General Medicine, Niigata University Medical and Dental Hospital, Japan)

Marilyn Urrutia-Pereira¹, Herberto Chong Neto², Pietro Nunes Rinelli¹, Laura Simon¹, Philippa Ellwood³, Luis García-Marcos⁴, Dirceu Solé⁵ (1.Federal University of Pampa, Brazil, 2.Federal University of Paraná, Brazil, 3.University of Auckland, New Zealand, 4.University of Murcia, Spain, 5.Federal University of São Paulo, Brazil)

Asami Minamibata^1,2, Taichiro Arimoto^1,2, Yoshinori Marunaka² (1.Department of Respiratory Medicine, Clinic, Kyoto Industrial Health Association, Japan, 2.Research Center for Clinical Respiratory Physiology, Research Institute for Clinical Physiology, Kyoto Industrial Health Association, Japan)

Michiyoshi Imaoka (Department of Medicine, Matsuyama Kinen Hospital, Japan)

Michiyoshi Imaoka (Department of Internal Medicine, Matsuyama Kinen Hospital, Japan)