Oral Session 2-12C ALL: Clinical (3)

[OS2-12C-2] Clinical significance of TP53 mutations in pediatric B cell acute lymphoblastic leukemia

Hiroo Ueno^1,2,3, Kenichi Yoshida¹, Yusuke Shiozawa^1,4, Yuka Iijima², Nobutaka Kiyokawa⁵, Yuichi Shiraishi⁶, Kenichi Chiba⁶, Hiroko Tanaka⁶, Tomoya Isobe⁴, Masafumi Seki⁴, Shunsuke Kimura⁴, Keisuke Kataoka^1,7, Hideki Makishima¹, Takao Deguchi⁸, Kentaro Ohki⁵, Atsushi Sato⁹, Hiroyuki Takahashi¹⁰, Yoshiko Hashii¹¹, Sadao Tokimasa¹², Junichi Hara¹³, Yoshiyuki Kosaka¹⁴, Koji Kato¹⁵, Takeshi Inukai¹⁶, Junko Takita^3,4, Toshihiko Imamura¹⁷, Satoru Miyano⁶, Atsushi Manabe¹⁸, Keizo Horibe², Seishi Ogawa¹, Masashi Sanada² (1.Path. & Tumor Biol., Kyoto Univ., Kyoto, Japan, 2.Clin. Res. Ctr., Nagoya Med. Ctr., Nagoya, Japan, 3.Pediatr. Kyoto Univ., Kyoto, Japan, 4.Pediatr. The Univ. of Tokyo, Tokyo, Japan, 5.Pediatr. Hematol. & Oncol. res. NCCHD, Tokyo Japan, 6.Human Genome Ctr., The Univ. of Tokyo, Tokyo, Japan, 7.Mol. Oncol., Natl. Cancer Ctr. Res. Inst., Tokyo Japan, 8.Pediatr. Mie Univ., Tsu, Japan, 9.Hematol. & Oncol. Miyagi Child. Hosp., Sendai, Japan, 10.Pediatr. Toho Univ., Tokyo, Japan, 11.Pediatr. Osaka Univ., Osaka, Japan, 12.Pediatr. Osaka City Univ., Osaka, Japan, 13.Pediatr. Hematol. & Oncol., Osaka City General Hosp., Osaka, Japan, 14.Hematol. & Oncol., Hyogo Pref. Children's Hosp., Kobe, Japan, 15.Children's Med. Ctr., Japanese Red Cross Nagoya First Hospital, Japan, 16.Pediatr. Yamanashi Univ., Kofu Japan, 17.Pediatr., Kyoto Pref. Univ. of Med., Kyoto, Japan, 18.Pediatr., Hokkaido Univ., Hokkaido, Japan)