[_BS] 優秀演題セッション

[BS-4] 網羅的ゲノム解析による高リスク肝芽腫の治療標的ODC1の同定
Comprehensive genetic and epigenetic analyses identify high expression of ODC1 as a therapeutic target in high-risk hepatoblastoma

Masahiro Sekiguchi¹, Masafumi Seki¹, Tomoko Kawai², Tomoya Isobe¹, Kenichi Yoshida³, Misa Yoshida¹, Ryota Shirai⁴, Ryota Souzaki⁵, Kenichi Kohashi⁶, Yuichi Shiraishi⁷, Noriko Hoshino⁸, Yusuke Sato⁹, Yoichi Fujii⁹, Kentaro Watanabe¹, Yuki Arakawa¹⁰, Katsuyoshi Koh¹⁰, Yasuhide Hayashi¹¹, Tomoaki Taguchi⁵, Motohiro Kato⁴, Masashi Sanada¹², Yukichi Tanaka¹³, Satoru Miyano⁷, Kenichiro Hata², Seishi Ogawa³, Junko Takita¹ (1.Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2.Department of Maternal-Fetal Biology, National Center for Child Health and Development, Tokyo, Japan, 3.Department of Pathology and Tumor Biology, School of Medicine, Kyoto University, Kyoto, Japan, 4.Children’s Cancer Center, National Center for Child Health and Development, Tokyo, Japan, 5.Department of Pediatric Surgery, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan, 6.Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, 7.Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 8.Department of Pediatric Surgery, Saitama Children’s Medical Center, Saitama, Japan, 9.Department of Urology, The University of Tokyo Hospital, Tokyo, Japan, 10.Department of Hematology/Oncology, Saitama Children’s Medical Center, Saitama, Japan, 11.Gunma Children’s Medical Center, Gunma, Japan, 12.Department of Advanced Diagnosis, Clinical Research Center, Nagoya Medical Center, Aichi, Japan, 13.Department of Pathology, Kanagawa Children’s Medical Center, Kanagawa, Japan)