[HT-04-1] Natural history of idiopathic REM behavior disorder: parasomnia vs. harbinger of synucleinopathies

Carlos Schenck (Minnesota Regional Sleep Disorders Center, Departments of Psychiatry, Hennepin County Medical Center, and University of Minnesota Medical School)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

[HT-04-2] レビー小体型認知症におけるレム期睡眠行動異常症と幻覚の関係

池田学¹, 鐘本英輝¹, 吉山顕次¹, 橋本衛², 數井裕光³ (1.大阪大学大学院医学系研究科精神医学分野, 2.熊本大学大学院生命科学研究部神経精神医学分野, 3.高知大学医学部　神経精神科学教室)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

[HT-04-3] パーキンソン病におけるレム睡眠行動異常症

野村哲志 (のむらニューロスリープクリニック神経内科)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

[HT-04-4] Aggressive behavior and dream contents in RBD: why and how?

Ki-Young Jung (Seoul National University College of Medicine)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

[HT-04-5] 特発性レム睡眠行動異常における臨床試験の準備と方向性

宮本雅之^1,2,3, 宮本智之⁴ (1.獨協医科大学看護学部看護医科学（病態治療）領域, 2.獨協医科大学病院脳神経内科, 3.獨協医科大学病院睡眠医療センター, 4.獨協医科大学埼玉医療センター脳神経内科)

REM sleep behavior disorder (RBD) now attracts much interest from the neurology community, mostly because RBD was incorporated with the revised clinical diagnostic criteria of dementia with Lewy bodies (DLB) as one of the core clinical features in 2017. It has been also well established that RBD often precedes other symptoms and signs of synucleinopathies. Under this circumstance, neurologists should understand what RBD is and to make an early diagnosis of RBD. However, historically RBD was classified as one of the parasomnias with a long history of sleep research, and patients with isolated/idiopathic RBD seek medical help for violent or potentially harmful behaviors during sleep. In this symposium, the speakers from different subspecialties are going to focus this dual nature of RBD. We expect the audience to obtain in-depth knowledge about RBD.

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