Multisystem atrophy (MSA) is a multi-system neurodegenerative disease of the cerebellum, pyramidal and extrapyramidal tract, and autonomic nervous system, which is characterized by the α-synuclein deposition in oligodendrocytes. There are still many unsolved issues about the pathological mechanism, and there is an urgent need to develop new therapeutic agents. Researches on MSA mainly cover the pathogenesis of α-synuclein, and includes disease-causing factors in DNA polymorphisms and microRNAs, and the dysfunction of neural networks by fMRI. It is important to confirm and discuss about the latest knowledge to develop further researches on MSA. Therefore, in this symposium, the latest research results on MSA in Japan will be presented, aiming discussion between speakers and participants to establish a new research goal on MSA.

Multisystem atrophy (MSA) is a multi-system neurodegenerative disease of the cerebellum, pyramidal and extrapyramidal tract, and autonomic nervous system, which is characterized by the α-synuclein deposition in oligodendrocytes. There are still many unsolved issues about the pathological mechanism, and there is an urgent need to develop new therapeutic agents. Researches on MSA mainly cover the pathogenesis of α-synuclein, and includes disease-causing factors in DNA polymorphisms and microRNAs, and the dysfunction of neural networks by fMRI. It is important to confirm and discuss about the latest knowledge to develop further researches on MSA. Therefore, in this symposium, the latest research results on MSA in Japan will be presented, aiming discussion between speakers and participants to establish a new research goal on MSA.

Multisystem atrophy (MSA) is a multi-system neurodegenerative disease of the cerebellum, pyramidal and extrapyramidal tract, and autonomic nervous system, which is characterized by the α-synuclein deposition in oligodendrocytes. There are still many unsolved issues about the pathological mechanism, and there is an urgent need to develop new therapeutic agents. Researches on MSA mainly cover the pathogenesis of α-synuclein, and includes disease-causing factors in DNA polymorphisms and microRNAs, and the dysfunction of neural networks by fMRI. It is important to confirm and discuss about the latest knowledge to develop further researches on MSA. Therefore, in this symposium, the latest research results on MSA in Japan will be presented, aiming discussion between speakers and participants to establish a new research goal on MSA.