[1P] 69 Alzheimer's Disease and Dementia

[1P-315] Effects of early tooth loss on the neuropathogenesis of Alzheimer's disease in adult Alzheimer’s model App^NL-G-F mice

*Suzuko Ochi¹, Kyoko Kajimoto¹, Kumiko Yamada², Takashi Saitou³, Takaomi C Saido⁴, Mitsuo Iinuma⁵, Kagaku Azuma⁶, Kin-ya Kubo⁷ (1. Asahi Univ, Dept, Pediatric Dent, Mizuho, Japan, 2. Nagoya Women’s Univ, Dept, Health and Nutrition, Aichi, Japan, 3. Nagoya City Univ, Grad Sch Medical Sci, Nagoya, Japan, 4. Lab, Proteolytic Neurosci, RIKEN CBS, Wako, Japan, 5. Asahi Univ, Mizuho, Jaoan, 6. UOEH, Med, Anat, Kitakyusyu, Japan, 7. Nagoya Women’s Univ, Grad Sch, Human Life Sci, Nagoya, Japan)

Keywords:Alzheimer’s disease,, Tooth loss, Amyloid-β,