[2P] 65 Neurodevelopmental disorders including ASD and ADHD

[2P-296] A novel mouse model for de novo mutation in CAMK2A identified in patients with intellectual disability

*miao pan^1,2, Pin-Wu Liu^1,3, Yukihiro Ozawa¹, Fumiko Arima-Yoshida⁴, Geyao Dong⁵, Masahito Sawahata⁵, Daisuke Mori^6,7, Hajime Fujii⁸, Shuhei Ueda^1,2, Hajime Narita^1,2,9, Ayumu Konno¹⁰, Hirokazu Hirai¹⁰, Norio Ozaki^6,11, Kiyofumi Yamada⁵, Hiroyuki Kidokoro⁹, Haruhiko Bito⁸, Hiroyuki Mizoguchi⁵, Ayako M.Watabe⁴, Shin-ichiro Horigane^1,2, Sayaka Takemoto-Kimura^1,2 (1. Dept. of Neuroscience I, Res. Inst. of Environmental Med., Nagoya Univ., Nagoya, Japan, 2. Molecular/Cellular Neuroscience, Nagoya Univ. Grad. Sch. of Med., Nagoya, Japan, 3. Grad. School of Med., Kyoto Univ., Kyoto, Japan, 4. Inst. of Clin. Med. and Res., Res. Ctr. for Med. Sci., The Jikei Univ. Sch. of Med., Chiba, Japan, 5. Dept. of Neuropsychopharmacology and Hosp. Pharm., Nagoya Univ. Grad. Sch. of Med., Nagoya, Japan, 6. Dept. of Psychiatry, Nagoya Univ. Grad. Sch. of Med., Nagoya, Japan, 7. Brain and Mind Res. Ctr., Nagoya Univ., Nagoya, Japan, 8. Dept. of Neurochemistry, Grad. Sch. of Med., The Univ. of Tokyo, Tokyo, Japan, 9. Dept. of Pediatrics, Nagoya Univ. Grad. Sch. of Med., Nagoya, Japan, 10. Dept. of Neurophysiology & Neural Repair, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan, 11. Dept. of Pathophysiology of Mental Disorders, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan)

Keywords:Neurodevelopmental disorder, Intellectual disability, CaMKII