[3P] 70 神経変性疾患

[3P-336] Oligonucleotides-based approaches for modulating FUS phase separation in ALS/FTLD intervention

*Moniruzzaman Mohammad¹、Fujioka Yusuke ¹、Takeuchi Akihide ²、Masuda Akio ³、Neya Masahiro ⁴、Okada Yohei ⁵、Ishigaki Shinsuke ¹ (1. Molecular Neuroscience Research Center, Shiga Univ of Medi Sci、2. Dept of Developmental Biology and Functional Genomics, Ehime Univ Grad Sch of Med 、3. Center for Neurological Diseases and Cancer, Nagoya Univ Grad Sch of Med 、4. KNC Laboratories Co., Ltd 、5. Institute for Medicine Science of Aging, Aichi Med Univ )

キーワード：ALS, Fused in Sarcoma (FUS), Liquid liquid phase separation (LLPS), Oligonucleotide therapeutics