[4O10m] Neurological diseases 3

[4O10m-01] α-synuclein is post-translationally modified by tyrosine hydroxylase in Parkinson’s disease, leading to a dopaminergic neurodegeneration.

*Sakiko Matsumoro¹, Mingyue Jin^1,2, Takashi Ayaki³, Keisuke Togawa¹, Toshifumi Takao⁴, Shinji Hirotsune¹ (1. Grad Sch Med, Osaka Metropolitan Univ, Osaka, Japan, 2. Sch Basic Med, Guilin Medical Univ, Guilin, China, 3. Grad Sch Med, Kyoto Univ, Kyoto, Japan, 4. Inst Prot Res, Osaka Univ, Osaka, Japan)

Keywords:Parkinson's disease, α-synuclein, Tyrosine hydroxylase, Post-tranlational modification