[2P] Drug Abuse and Addiction

[2P-142] Impairment of nicotine-induced behavioral changes in L-DOPA receptor gene (Gpr143)-deficient mice, and genetic associations of single nucleotide polymorphisms in the GPR143 gene with severity of nicotine dependence in Japanese in dividuals

*Daiki Masukawa¹, Daisuke Nishizawa², Yuka Kasahara¹, Satoshi Kitamura¹, Kaori Kanai¹, Tatsuo Hashimoto¹, Junko Hasegawa³, Naomi Sato^3,4, Kyoko Nakayama², Fumihiko Tanioka⁵, Haruhiko Sugimura⁴, Kazutaka Ikeda², Yoshio Goshima¹ (1.Dept. Mol. Pharmacol. and Neurobiol., Yokohama, Japan, 2.Tokyo Metropolitan Inst., 3.Dept Clinical Nursing Hamamatsu Univ. Sch. of Medecine, 4.Dept Tumor Pathology Hamamatsu Univ. Sch. of Medecine, 5.Dept Pathol, Iwata City Hospital)