ALPS Poster Session 2

[ALPSp2-29] Post-irradiation recovery time strongly influences the skin barrier function and drug absorption after fractional CO₂ laser treatment

*Chi-Feng Hung¹, En-Li Chen², Jia-You Fang² (1. Fu Jen Catholic University, 2. Chang Gung University)

The present study aimed to explore the influence of recovery time after fractional CO2 laser irradiation on the enhancement of drug penetration. The fractional laser produced microchannels of about 150 μm in diameter and 25 μm in depth that were surrounded with thermal coagulation. The bright-field imaging indicated that the micropores were progressively closed during the recovery period but had not completely closed even after a 16-h recovery.