Session 3

[BISC3-01(Invited)] Quantitative Diffuse Reflectance Spectroscopy for Noninvasive Retrieval of Human Total Hb and HbA1c Contents

Ying-Yu Chen¹, Tzyy-Wei Fu¹, Chia-Te Chen^2,3, Hsiu-Chi Cheng^3,4,5, *Sheng-Hao Tseng^1,6 (1. Department of Photonics, National Cheng-Kung University, 2. Department of Nursing, National Cheng Kung University Hospital, 3. Department of Internal Medicine, National Cheng Kung University Hospital, 4. Institute of Clinical Medicine, National Cheng Kung University, 5. Institute of Molecular Medicine, National Cheng Kung University, 6. School of Dentistry, College of Dental Medicine, Kaohsiung Medical University)

We demonstrate here a compact, handheld diffuse reflectance spectroscopy device for non-invasive measurement of hemoglobin and HbA1c in human skin, validated on 16 patients, showing high correlation (r=0.886 and r=0.918) with blood test results.