[29P01] 代謝/ADMET, PK/PD/薬物間相互作用

Mon. Mar 29, 2021 9:00 AM - 6:00 PM [Room P01] Poster Presentation (Online)

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[29P01-246] Effect of antibiotics on testosterone 6β-hydroxylation mediated by human cytochrome P450 3A subfamilies

○Risa Ishii¹, Toshiro Niwa¹ (1. Sch. Pharm., Shujitsu Univ.)

[29P01-247] Effect of endogenous steroid hormones and related compounds on cortisol 6β-hydroxylation mediated by human cytochrome P450 3A subfamilies

○Misaki Tani¹, Kyoko Kato¹, Ayaka Okamoto¹, Toshiro Niwa¹ (1. Sch. Pharm., Shujitsu Univ.)

[29P01-248] Effect of endogenous steroid hormones and human cytochrome P450 (CYP) 3A4 inhibitors on testosterone 6β-hydroxylation mediated by CYP3A subfamilies

○Hinako Kawasaki¹, Ayaka Okamoto¹, Manami Toyota¹, Toshiro Niwa¹ (1. Sch. Pharm., Shujitsu Univ.)

[29P01-249] Effect of antidepressants including selective serotonin reuptake inhibitors on human cytochrome P450 2D6-mediated dopamine formation from p-tyramine

○Yurina Michihiro¹, Juri Arima¹, Shizuya Sugimoto¹, Toshiro Niwa¹ (1. Sch. Pharm., Shujitsu Univ.)

[29P01-250] Effect of endogenous steroid hormones and related compounds on progesterone hydroxylation mediated by human cytochrome P450 3A subfamilies

○Mayu Tanaka¹, Manami Toyota¹, Toshiro Niwa¹ (1. Sch.Pharm.,Shujitsu Univ.)

[29P01-251S] Generation of Caco-2 cells stably expressing drug metabolizing enzymes using the PITCh system

○Naoki Yamada¹, Ryosuke Negoro¹, Yusuke Kono², Takuya Fujita^1,2 (1. Graduate School of Pharmaceutical Sciences, Ritsumeikan University, , 2. R-GIRO, Ritsumeikan University)

[29P01-252S] Study on miR-34a-induced epithelial-mesenchymal transition in alveolar epithelial cells.

○Shinnosuke Takenaka¹, Masashi Kawami¹, Ryoko Yumoto¹, Mikihisa Takano¹ (1. Grad. Sch. Biomed. Health Sci., Hiroshima Univ.)

[29P01-253] Association of Rh C glycoprotein with epithelial-mesenchymal transition in alveolar epithelial cells

○Masashi Kawami¹, Ryoko Yumoto¹, Mikihisa Takano¹ (1. Grad. Sch. Biomed. Health Sci., Hiroshima Univ.)

[29P01-254S] Development of simultaneous in vivo measurement using LC-MS/MS of multiple receptor occupancy targeted for antipsychotics

○Wataru Sasaki¹, Gaku Akashita¹, Eriko Nakatani¹, Takashi Okura¹ (1. Faculty of Pharma-Science, Teikyo Univ.)

[29P01-255] A case report: Pharmacy pharmacists prevented adverse effects due to a drug-drug interaction via BCRP

○Miki Nishimura¹, Kaori Okada¹, Naotaka Hashiguchi¹, Yuichiro Yamamoto^1,2 (1. Apple pharmacy, 2. I&H Co., Ltd.)

[29P01-256] Drug–endogenous substrate interactions on P-glycoprotein for testosterone

○Kenta Mizoi¹, Reiko Takahashi¹, Saori Takahashi¹, Takuo Ogihara¹ (1. Faculty of Pharmacy, Takasaki University of Health and Welfare)

[29P01-257S] Effect of bioavailability of the substrate drug in predicting drug interaction by physiologically based pharmacokinetic analysis.

○Maho Ishimoto¹, Sachiko Yugeta¹, Kenjiro Okubo¹, Runa Kawamoto¹, Motohiro Kato¹, Yoshiaki Yamagishi¹, Toshiyuki Kudo¹, Kiyomi Ito¹ (1. Faculty of Pharmacy, Musashino University.)

[29P01-258] A prescription survey on drug-drug interaction for miconazole gel formula over 75 years geriatric patients using large claims data

○Kumiko Shimamura¹, Kenji Momo², Tadanori Sasaki³ (1. Department of Pharmacy, Showa University Dental Hospital, 2. Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, 3. Department of Pharmacy, Showa University Graduate School)

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