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[2P-394] Effects of p53 tetramerization domain mutants found in Li-Fraumeni syndrome on hetero-oligomerization and transcriptional activity

Kanno Madoka1, Imagawa Toshiaki1,2, Toguchi Yu1, Kamada Rui1,2, Sakaguchi Kazuyasu1,2 (1.Lab. of Biol. Chem., Grad. Sch. of Chem. Sci. & Eng., Hokkaido Univ., 2.Lab. of Biol. Chem., Dept. of Chem., Fac. of Sci., Hokkaido Univ.)

Tumor suppressor protein p53, Mutation, Transcriptional activity, Li-Fraumeni syndrome, Oligomerization

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