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[4P-123] (4T10p-11)E6-AP/UBE3A Protein Acts as a Ubiquitin Ligase toward SOX9 Protein and regulates endochondral ossification

Hattori Takako1, Kishino Tatsuya2, Stephen Shelley3, Eberspaecher Heidi3, Maki Sayumi4, Takigawa Masaharu1, de Crombrugghe Benoit3, Yasuda Hideyo3,4 (1.Dept. of Biochem. Mol. Dent., Okayama Univ. Grad. Schl. of Med. Dent. Pharm. Sci., 2.Div. Func. Genom., Cent. for Front. Sci., Nagasaki Univ., 3.Univ. Texas, M.D. Anderson Cancer Center,, 4.Nippon Flour Mills Co. Ltd.)

ユビキチンリガーゼ, 軟骨細胞, プロテオミクス解析, 内軟骨性骨形成

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