2:45 PM - 3:45 PM

[2P-356] Enhancement of α-secretase activity and suppression of β-secretase activity by novel native polyphenols.

^○Momoka Kinoshita^1,2, Junya Fukuda², Kaori Watanabe¹, Yuma Hori¹, Daisuke Hatta¹, Yuki Kawano¹, Masashi Asai^1,2, Keiro Shirotani^1,2, Takashi Tanaka^2,3, Nobuhisa Iwata^1,2 (1.Dept. of Genome-based Drug Discovery, Grad. Sch. of Biomed. Sci., Nagasaki Univ., 2.Dept. of Genome-based Drug Discovery, Sch. of Pharm. Sci., Nagasaki Univ., 3.Dept. of Natural Product Chem., Grad. Sch. of Biomed. Sci., Nagasaki Univ.)

アルツハイマー病, アミロイドβペプチド, ADAM, BACE1, ポリフェノール