The Japanese Biochemical Society

The 89th Annual Meeting of JBS

The 89th Annual Meeting of JBS

Sep 25, 2016 - Sep 27, 2016
Sendai International Center/ Kawauchi Campus, Tohoku University

3:40 PM - 4:40 PM

[3P-070] Hyaluronan production regulates metabolic and cancer stem-like properties of breast cancer cells via hexosamine biosynthetic pathway-coupled HIF-1 signaling

○Tomomi Izumikawa1, Theerawut Chanmee1, Pawared Ontong1, Nobutoshi Mochizuki1, Miho Higashide1, Manatsanan Khansai1,2, Chatchadawalai Chokchaitaweesuk1, Kazuki Nakajima3, Ikuko Kakizaki4, Prachya Kongtawelert2, Naoyuki Taniguchi5, Naoki Itano1 (1.Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University, 2.Thailand Excellence Center for Tissue Engineering and Stem Cells, Department of Biochemistry, Faculty of Medicine, Chiang Mai University, 3.Center for Research Promotion and Support, Fujita Health University, 4.Department of Glycotechnology, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, 5.Disease Glycomics Team, Systems Glycobiology Research Group, Global Research Cluster, RIKEN-Max Planck Joint Research Center, RIKEN)

hyaluronan, Cancer stem cells, HBP, HIF-1α, GFAT-1

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