Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

Shingo Sakamoto

[1P-357] Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

^○Shingo Sakamoto¹, Toru Komatsu¹, Rikiya Watanabe², Yoku Cho³, Taiki Inoue¹, Mitsuyasu Kawaguchi⁴, Hidehiko Nakagawa⁴, Takaaki Ueno⁵, Takuji Okusaka⁶, Kazufumi Honda⁷, Hiroyuki Noji^3,8, Yasuteru Urano^1,9,10 (1.Grad. Sch. Pharm. Sci., The Univ. Tokyo, 2.RIKEN, 3.Grad. Sch. Eng., The Univ. Tokyo, 4.Grad. Sch. Pharm. Sci., Nagoya City Univ., 5.Osaka Dent. Univ., 6.Natl. Cancer Ctr. Hosp., 7.Natl. Cancer Ctr. Res. Inst., 8.ImPACT, 9.Grad. Sch. Med., The Univ. Tokyo, 10.AMED-CREST)

キーテクノロジー：蛍光プローブ

蛍光プローブ、マイクロチャンバー、１分子酵素活性検出、アイソザイム、膵臓癌

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The 92nd Annual Meeting of JBS

[1P-357] Single Enzyme Activity-based Protein Profiling - A Methodology for Ultra-sensitive Detection of Disease-related Alterations of Enzymatic Activities

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