The Japanese Biochemical Society

[P-756] TNF-α enhances TGF-β-induced endothelial-to-mesenchymal transition via TGF-β signal augmentation

Ikumi Wakabayashi1,2, Yasuhiro Yoshimatsu1,3, Shiori Kimuro1, Naoya Takahashi1, Kazuki Takahashi1, Fumiko Ito2, Miho Kobayashi1, Katarzyna A. Inoue1, Kohei Miyazono4, Tetsuro Watabe1 (1.Department of Biochemistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University,, 2.Laboratory of Cardiovascular Medicine, Tokyo University of Pharmacy and Life Sciences, 3.Division of Pharmacology, Graduate School of Medical and Dental Sciences, Niigata University, 4.Department of Molecular Pathology, Graduate School of Medicine, The University of Tokyo)

キーテクノロジー:癌微小環境の細胞レベルでの構築

TGF-β、TNF-α、EndMT、Smad2/3シグナル

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