The Japanese Biochemical Society

[2P-122] Integrated experimental-theoretical approaches to deciphering how H179Y substitution affects the biological functions of PRMT1

Yuan Yao 1, Koichiro Kako2, Kaori Motomura3, Jundal Kim4, Akiyoshi Fukamizu3,5 (1.Doctorial Programs in Human Biology, University of Tsukuba, 2.Faculty of Life and Environmental Sciences, 3.TARA Center, 4.Institute of National Medicine (INM), University of Toyama, 5.Japan Agency for Medical Research and Development (AMED))

キーテクノロジー:Theo-Exp. Analysis

Arginine methylation、in vitro methylation assay、MD simulation、humanized mouse、bioinformatics

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