[1P-374] Adaptor protein 3BP2 regulates signal transduction through CARD9.

^〇Ayumi Tsubokawa^1,2, Kazuyasu Chihara^1,3, Yuri Chihara¹, Kenji Takeuchi^1,3, Shigeharu Fujieda^2,3, Kiyonao Sada^1,3 (1.Department of Genome Science and Microbiology, Faculty of Medical Sciences, University of Fukui, 2.Department of Otorhinolaryngology Head & Neck Surgery, Faculty of Medical Sciences, University of Fukui, 3.Life Science Innovation Center, University of Fukui)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-375(1T07a-11)] Development of a peptide-based compound that inhibits osteoclastogenesis by targeting TRAF6 to modulate its downstream signaling.

^〇Masataka Anzai¹, Miho Takahashi¹, Keizo Nishikawa², Hiroaki Sakurai³, Jun-ichiro Inoue⁴, Kiyotaka Nishikawa¹ (1.Lab. of Mol. Life Sci., Facult. of Life and Med. Sci., Doshisha Univ., 2.Lab. of Cell Biol. and Metab. Biochem., Facult. of Life and Med. Sci., Doshisha Univ., 3.Dep. of Cancer Cell Biol., Facul. of Pharma. Sci., Univ. of Toyama, 4.Res. Platform Office, The Inst. of Med. Sci., The Univ. of Tokyo)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-376] Regulation of cancer cell motility through co-operative transcriptional regulation by Smad3, a TGF-β signaling molecule, and Ets2

^〇Yuka Itoh¹, Chiho Omata¹, Kunio Miyake¹, Masao Saitoh¹, Keiji Miyazawa¹ (Graduate School of Medicine, University of Yamanashi)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-377] Positive regulation of TGF-β-induced osteoblastic differentiation in mesenchymal stem cell by CTGF

^〇Hironori Yoshida¹, Karen Abe¹, Kanna Asanuma¹, Emiko Kikuchi¹, Seiji Yokota², Akira Ishisaki², Kazuro Satoh¹, Naoyuki Chosa² (1.Division of Orthodontics, Department of Developmental Oral Health Science, Iwate Medical University , 2.Division of Cellular Biosignal Sciences, Department of Biochemistry, Iwate Medical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-378(1T07a-10)] Novel regulatory mechanisms of the MDM2-p53 pathway modulated by the ubiquitin ligase MKRN1

^〇Tatsuya Shimada¹, Yusuke Hirata¹, Takuya Noguchi¹, Atsushi Matsuzawa¹ (Lab. of Health Chem., Grad. Sch. of Pharmaceut. Sci., Tohoku Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-379] Activation of the YAP signaling pathway by Prip deficiency promotes renal fibrosis

^〇Meiqun Yuan¹, Tomomi Sano², Akiko Mizokami³, Jing Gao⁴, Takashi Kanematsu² (1.Dept. Cell Biol. Aging Sci. & Pharmocol., Grad. Sch. Dent. Sci., Kyushu Univ., 2.Dept. Cell Biol. Aging Sci. & Pharmocol., Facul. Dent. Sci., Kyushu Univ., 3.OBT Res. Ctr., Facul. Dent., Sci., Kyushu Univ., 4.Dept. Mol. Cell. Biochem., Facul. Dent. Sci., Kyushu Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-380] Application of the Mirabody technology, a receptor agonist design technology, to epidermal growth factor receptor (EGFR)

^〇Azusa Nitta¹, Fumiya Mizutani¹, Emiko Mihara¹, Takao Arimori¹, Junichi Takagi¹ (IPR, Osaka Univ.)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-381(1T07a-12)] Activation of STING requires cholesterol-mediated clustering at the TGN

^〇Haruka Kemmoku¹, Kanoko Takahashi¹, Kojiro Mukai¹, Yoshihiko Kuchitsu¹, Kenichi Suzuki², Tomohiko Taguchi¹ (1.Tohoku Univ., Graduate School of Life Sciences, 2.Gifu Univ., Institute for Glyco-Core Research)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-382] CRL4^CRBN neosubstrates involved in antiangiogenic activity of thalidomide and immunomodulatory drugs

^〇Tomoko Asatsuma-Okumura¹, Yoshiko Iwai¹, Hiroshi Handa², Takumi Ito² (1.Nippon Medical School, 2.Tokyo Medical University)

The 96th Annual Meeting of the Japanese Biochemical Society

[1P-383] Mechanism of cell fate decision for inflammatory senescence induced by sustained activation of NF-kB.

^〇Shou Soeda¹, Keita Matsuda¹, Yoko Takada², Jun Adachi², Mariko Okada¹ (1.Institute for Protein Research, Osaka University, 2.National Institute of Biomedical Innovation, Health and Nutrition)

The 96th Annual Meeting of the Japanese Biochemical Society