The Japanese Biochemical Society

[2P-296] Uncovering oligomeric assembly of LAMP2A, a receptor of chaperone-mediated autophagy, in mammalian cells

Tatsuro Seike1, Kazue Terasawa2,3, Sakamoto Kensaku4,8, Kazumasa Ohtake4,5, Tohru Terada6, Tetsuro Watabe3, Shigeyuki Yokoyama7,8, Miki Yokoyama3 (1.Department of Periodontology, Tokyo Medical and Dental University, 2.LiberoThera, 3.Department of Biochemistry, Tokyo Medical and Dental Universtiy, 4.Laboratory for Nonnatural Amino Acid Technology, RIKEN, 5.Department of Electrical Engineering and Biosciences, Waseda University, 6.Department of Biotechnology, The University of Tokyo, 7.Department of Structural Biology and Biochemistry, Tokyo Medical and Dental Universtiy, 8.Shinshu University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-297] Regulation of phase-separated p62 body by PP2A-PPP2CA-PPP2R5E phosphatase

JIACHEN LI1, Hideaki Morishita1,3, Satoko Komatsu(Hirota)1, Satoshi Waguri2, Yoshinobu Yichimuara1, Masaaki Komatsu1 (1.Jutendo University Graduate School of Medicine, 2.Department of Anatomy and Histology Fukushima Medical University, 3.Graduate School of Medical Sciences, Kyushu University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-298(1T10a-05)] Autophagy inducer screening mediated by Lysosomal clustering and the degradation analysis of α-Synuclein aggregation

Yuki Date1,2, yukiko sasazawa2,3,4, Mitsuhiro Kitagawa2,3, Hideyuki Saya5, Masaya Imoto3, Eisuke Itakura6, Shinji Saiki7,8, Nobutaka Hattori7,9 (1.Department of Biology, Graduate school of Science and Engineering, Chiba University, 2.Department of Neurology, Juntendo University School of Medicine, 3.Juntendo University School of Medicine Juntendo University Graduate School of Medicine, 4.Research Institute for Diseases of Old Age, 5.Fujita medical university, cancer centar, 6.Department of Biology, Graduate school of Science, Chiba University, 7.Department of Neurology, Juntendo University School of Medicine, 8.Department of Neurology, Tsukuba University School of Medicine, 9.Neurodegenerative Disorders Collaborative Laboratory, RIKEN Center for Brain Science, Japan)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-300] Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response

Yoshinobu Ichimura1, Ryo Ikeda1,2, Daisuke Noshiro3, Hideaki Morishita1,8, Shuhei Takada1, Shun Kageyama1, Yuko Fujioka3, Tomoko Funakoshi1, Satoko Komatsu-Hirota1, Ritsuko Arai4, Elena Ryzhii4, Manabu Abe5, Tomoaki Koga6, Hozumi Motohashi7, Mitsuyoshi Nakao6, Kenji Sakimura5, Arata Horii2, Satoshi Waguri4, Nobuo N. Noda3, Masaaki Komatsu1 (1.Department of Physiology, Juntendo University Graduate School of Medicine, 2.Department of Otolaryngology Head and Neck Surgery, Niigata University Graduate School of Medical and Dental Sciences, 3.Institute for Genetic Medicine, Hokkaido University, 4.Department of Anatomy and Histology, Fukushima Medical University School of Medicine, 5.Department of Animal Model Development, Brain Research Institute, Niigata University, 6.Department of Medical Cell Biology, Institute of Molecular Embryology and Genetics, Kumamoto University, 7.Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, 8.Graduate School of Medical Sciences, Kyushu University)

The 96th Annual Meeting of the Japanese Biochemical Society

[2P-304] Investigation of autophagic cell death induced by Ridaifen-B

Yuta Semba1, Amane Yoneoka2, Kyoka Komukai2, Takatsugu Murata2, Isamu Shiina2, Takahisa Shinomiya1, Shunsuke Takahashi1, Yukitoshi Nagahara1 (1.Dept. of Sci. Eng., Tokyo Denki Univ., 2.Dept. of Sci., Tokyo Univ. of Sci.)

The 96th Annual Meeting of the Japanese Biochemical Society