[3P-0440] Generation and behavioral analysis of PCDH15-deficient model mice

〇Ryosuke Ikeda^1,2, Masahito Sawahata², Itaru Kushima^1,3, Yuko Arioka^1,4, Taku Nagai², Kiyofumi Yamada², Daisuke Mori^1,5, Norio Ozaki¹ (1.Dept. of Psychiatry, Grad. Sch. of Med., Nagoya Univ., 2.Dept. of Neuropsychopharmacology and Hospital Pharmacy, Grad. Sch. of Med., Nagoya Univ., 3.Medical Genomics Center, Nagoya Univ. Hosp., 4.Center for Advanced Medicine and Clinical Research, Nagoya Univ. Hosp., 5.Brain and Mind Research Center, Nagoya Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0441] Generation and behavioral analysis of RELN-deficient model mice

〇Daisuke Mori^2,5, Masahito Sawahata¹, Ryosuke Ikeda^1,2, Itaru Kushima^2,3, Yuko Arioka^2,4, Taku Nagai¹, Kiyofumi Yamada¹, Norio Ozaki² (1.Neuropsychopharmacology and Hospital Pharmacy, Nagoya Univ., 2.Psychiatry, Nagoya Univ., 3.Medical Genomics Center, Nagoya Univ. Hospital, 4.Center for Advanced Medicine and Clinical Research, Nagoya Univ. Hospital, 5.Brain and Mind Research Center, Nagoya Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0442] Development of induced pluripotent stem cell model of bipolar disorder derived from an Okinawan pedigree with a potential genetic component

〇Gakuya Takamatsu^1,2, Kumiko Yanagi⁶, Yoko Manome⁵, Kae Koganebuchi⁴, Junsoku Lee¹, Kanako Toyama¹, Mutsumi Isa³, Kotaro Hattori^7,8, Tomoko Hayakawa⁹, Chikako Miyauchi Hara⁵, Minami Hasegawa⁵, Dimitar Dimirov¹⁰, Tomoyuki Takahashi¹⁰, Hiroshi Kunugi⁷, Tsuyoshi Kondo², Ryosuke Kimura³, Tadashi Kaname⁶, Hirotaka James Okano⁵, Masayuki Matsushita¹ (1.Dept. of Mol. and Cell. Physiology, Grad. Sch. of Med., Univ. of the Ryukyus, 2.Dept. of Neuropsychiatry, Grad. Sch. of Med., Univ. of the Ryukyus, 3.Dept. of Human Biol. and Anatomy, Grad. Sch. of Med., Univ. of the Ryukyus, 4.Res. Ctr. for Advanced Med. Sciences, Fac. of Med., Univ. of the Ryukyus, 5.Div. of Regenerative Med., Jikei Univ., 6.Dept. of Genome Med., Natl. Ctr. for Child Hlth. and Develop., 7.Dept. of Mental Disorder Research, Natl. Inst. of Neurosci., 8.Med. Genome Cente., Natl. Inst. of Neurosci., 9.Div. of Clin. Pharmacology, Dept. of Pharmacol., Jichi Med. Univ., 10.Cell. and Mol. Syn. Func. Uni., Okinawa Inst. of Sci. and Tech. Grad.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0443(1PW-03-3)] Novel technology for generating region-specific and functional neurons from iPSCs to model neurological diseases

〇Tsukika Sato¹, Kent Imaizumi¹, Hideyuki Okano¹ (1.Dept. of Physiology.,Grad. Sch. of Med.,Univ of Keio)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0444(4W-10-2)] Direct conversion of Parkinson's disease model marmoset fibroblasts into neurons and in vitro pathological analysis

〇Akisa Nemoto¹, Reona Kobayashi^1,2, Seiji Shiozawa¹, Hideyuki Okano^1,2 (1.Dept. of Physiol., Sch. of Med., Keio Univ., 2.RIKEN Center for Brain Science, Wako, Japan)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0445] LRRK2 is associated with enteric neurogenesis through Wnt pathway

〇Ryuichi Motokawa¹, Tatsunori Maekawa¹, Takafumi Ichikawa¹ (1. Kitasato University Graduate School of Medicine)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0446(3AW-20-5)] α-Synuclein aggregation by the alteration of biomembrane homeostasis

〇Yuzuru Imai^1,2, Akio Mori², Tsuyoshi Inoshita¹, Kahori Shiba¹, Hongrui Meng¹, Nobutaka Hattori^1,2 (1.Dept. of Parkinson's, Grad. Sch. of Medi., Juntendo Univ., 2.Dept. of Neurol, Sch. of Medi., Juntendo Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0447] Parkinson's disease-associated genes regulate the quality control of α-synuclein at presynapses through the endo-lysosomal pathway

〇Tsuyoshi Inoshita^1,2, Jun Yi Liu², Daisuke Taniguchi², Changxu Cui³, Masashi Takanashi ², Yuzuru Imai^2,3, Nobutaka Hattori^1,2,3 (1.Dept. of MS., Med., Juntendo Univ., 2.Dept. of Neurol., Med., Juntendo Univ., 3.Dept. of parkinson., Med., Juntendo Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0448] Parkinson's desease related protein VPS13C involved in autophagy

〇Kahori Shiba¹, Tsuyoshi Inoshita¹, Hongrui Meng², Jun Ogata², Yuzuru Imai², Nobutaka Hattori^1,2 (1.Dept. of Neurol, Sch. of Medi., Juntendo Univ., 2.Dept. of Neurol, Sch. of Medi., Juntendo Univ.)

The 42nd Annual Meeting of the Molecular Biology Society of Japan

[3P-0449] Novel Drosophila model for Parkinsonʼs disease targeting of Phosphoglycerate kinase

〇Joe Shimizu¹, Takashi Kasai², Hideki Yoshida^3,4, Masamitsu Yamaguchi^3,4 (1.Dept. of Appl. Advan., Kyoto Inst. of Tech.,, 2.Dept. of Neurol., Grad. Sch. of Med., Kyoto Pref. Univ. of Med.,, 3.Dept. of Appl Biology, Kyoto Inst. of Tech.,, 4.Insect Biomed. Res.Center, Kyoto Inst. of Tech)

The 42nd Annual Meeting of the Molecular Biology Society of Japan