The Molecular Biology Society of Japan

[1P-0145] IRAK1, a shared component of Toll-like receptor/IL-1 receptor pathways, activates Wnt/β-catenin signalling pathway via the interaction of its PPPSP motif with Axin1.

○Yasuhiro Mimura1, Masako Inui1, Masanori Taira2, Kohei Otsubo3, Hiroki Hikasa1 (1.Dept. of Biochem., Sch. of Med., UOEH, 2.Dep. of Life Sci., Inst. of Sci. and Eng., CHUO univ., 3.Res. Inst. for Dis. of the Chest, Grad. Sch. of Med. Sci., Univ. of Kyushu)

Inflammation, Interleukin 1 receptor-associated kinase 1, Wnt/β-catenin pathway

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