[1P-0325] The hepatic metabolic abnormalities involved in the initiation of NAFLD are caused by elevated amount of skatole in the gastrointestinal tract

○Ryosuke Tomatsu¹, Yasutake Tanaka², Takuma Nose³, Kana Yuasa¹, Satoshi Ishizuka³, Hidehisa Shimizu^1,4 (1.Grad. Sch. of Nat Sci. and Tech., Shimane Univ., 2.Fac. of Agr., Grad. Sch., Kyushu Univ., 3.Res. Fac. of Agr., Hokkaido Univ., 4.Acad. Asse., Shimane Univ. )

Intestinal bacteria metabolite, Tryptophan metabolite, Indole compounds, Deoxycholic asid, Non-alcoholic fatty liver disease