Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice

○Yoshitaka Fujihara, Yonggang Lu, Taichi Noda, Asami Oji, Tamara Larasati, Kanako Kita, Zhifeng Yu, Ryan M. Matzuk, Martin M. Matzuk, Masahito Ikawa

[3P-0229] Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice

○Yoshitaka Fujihara^1,2,3, Yonggang Lu², Taichi Noda², Asami Oji², Tamara Larasati², Kanako Kita², Zhifeng Yu³, Ryan M. Matzuk³, Martin M. Matzuk³, Masahito Ikawa² (1.Dept. of Bios and Gen., NCVC, 2.RIMD., Osaka Univ., 3.BCM)

CRISPR-Cas9, Fertilization, IZUMO1, Infertility

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The 43rd Annual Meeting of the Molecular Biology Society of Japan

[3P-0229] Spermatozoa lacking Fertilization Influencing Membrane Protein (FIMP) fail to fuse with oocytes in mice

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