[1P-0285] Whole-exome sequence analysis for Japanese oral squamous cell carcinomas.

○Yuko Osawa¹, Kazuyoshi Hosomichi³, Masahiro Uchibori¹, Yoshihide Ota¹, Atsushi Tajima³, Minoru Kimura² (1.Department of Oral and Maxillofacial Surgery,Tokai University School of Medicine, 2.The Institute of Medical Sciences, Tokai University, 3.Department of Bioinfomatics and Genomics,Graduate School of Advanced Preventive Medical Sciences, Kanazawa University.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0286] Establishment and Characterization of Luminal High-Osteolytic Breast Cancer Cell Lines Using Intra-Caudal Arterial Injection

○YUXUAN HAN^1,2, Jun Nakayama^2,3, Yusuke Hayashi ¹, Seongmoon Jeong¹, Mitsuru Futakuchi ⁴, Emi Ito⁵, Shinya Watanabe⁵, Kentaro Semba^1,5 (1.Dept. of Life Sci. and Med. Biosci., Waseda Univ., 2.Japan Society for the Promotion of Science, 3.Division of Cellular Signaling, National Cancer Center Research Institute, 4.Dept. of Pathology, Nagasaki Univ., 5.TR Center, Fukushima Med. Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0287] Evaluation of the antiproliferative effects of the HASPIN inhibitor CHR-6494 in breast cancer cell lines

○Hisayo Nishida-Fukuda¹, Keizo Tokuhiro¹, Hiroaki Matsushita², Yukio Ando², Morimasa Wada³, Hiromitsu Tanaka³ (1.Dept. Genome Editing, Inst. of Biomed. Sci., Kansai Med. Univ., 2.Dept. of Amyloidosis Res., Fac. of Pharm. Sci., Nagasaki Int'I. Univ., 3.Lab. of Mol. Biol., Fac. of Pharm. Sci., Nagasaki Int'I. Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0288] Pan-cancer analysis reveals possible involvement of non-coding recurrent mutations in cancer pathogenesis

○Chie Kikutake¹, Suyama Mikita¹ (1.Division of Bioinformatics, MIB, Kyushu Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0289] Functional involvement of ubiquitin-like protein ISG15 in tumorigenesis

○Keisuke Inuyama^1,2, Keiji Okamoto¹, Rie Fujiwara^1,2, Toshiro Migita¹, Hiroyuki Seimiya^1,2 (1.Div. Mol. Biother., Cancer. Chemother. Ctr., JFCR, 2.Dept. Comp. Biol. Med. Sci., Grad. Sch. Front. Sci. Univ. Tokyo)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0290] Nuclear translocation of FAK promotes tumor metastasis of small cell lung cancer.

○Aki Iwamoto¹, Takamasa Uekita¹ (1.Dept.of App. Chemi., National Defense Academy)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0291] Distinct regulation of tumor suppressor genes by the transcription factor E2F in epithelial cells

○Genki Kishi¹, Tomoko Warita¹, Kiyoshi Ohtani¹ (1.Dept. of Biomed. Chem., Grad. Sch. of Sci. Tec., Kwansei Gakuin Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0292] Functional analyses of the NRF3-CTGF pathway for pancreatic cancer malignant transformation

○Takuto Michihara¹, Tsuyoshi Waku², Akira Kobayashi^1,2 (1.Grad. Sch. of Life and Med.Sci.,Doshisha Univ., 2.Fac. of Life and Med.Sci.,Doshisha Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0293] Dynamic regulation of pro- and anti-apoptotic genes induced by the cytotoxic activity of Berberis vulgaris L. var. asperma against multi-drug resistant human-derived breast adenocarcinoma cells

○Glenn G Oyong¹, Mary Stephanie S Carranza², Maria Carmen S Tan² (1.Molecular Science Unit Laboratory, Center for Natural Science and Environmental Research, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines, 2.Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila 1004, Philippines)

The 43rd Annual Meeting of the Molecular Biology Society of Japan

[1P-0294] NRF3 regulates cholesterol metabolism by coordinating SREBP2 function and LDL uptake.

○Yuri Atsumi¹, Toru Hagiwara¹, Natsuko Tamura¹, Yasuomi Urano², Tsuyoshi Waku², Akira Kobayashi^1,2 (1.Grad. Sch. of Life and Med. Sci., Doshisha Univ., 2.Fac. of Life and Med. Sci., Doshisha Univ.)

The 43rd Annual Meeting of the Molecular Biology Society of Japan