[1P-202] HNRNPU Facilitates Antibody Class Switch Recombination through C-NHEJ Promotion and R-loop Suppression

^○Ahmed M. Refaat^1,2, Nasim A. Begum¹, Afzal Husain³, Mikiyo Nakata¹, Hidetaka Kosako⁴, Tasuku Honjo¹ (1.Department of Immunology and Genomic Medicine, Center for Cancer Immunotherapy and Immunobiology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan, 2.Department of Zoology, Faculty of Science, Minia University, El-Minia, 61519, Egypt, 3.Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, Aligarh, Uttar Pradesh 202002, India, 4.Division of Cell Signaling, Institute of Advanced Medical Sciences, The University of Tokushima, Tokushima 770-8503, Japan)