[1P-345] iPSC reprogramming-mediated aneuploidy rescue in the major autosomal trisomy syndromes

^○Silvia Natsuko Akutsu¹, Tatsuo Miyamoto², Daiju Oba³, Keita Tomioka^1,4, Hiroshi Ochiai⁵, Hirofumi Ohashi³, Shinya Matsuura¹ (1.Department of Genetics and Cell Biology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima 734-8553, Japan, 2.Department of Molecular and Cellular Physiology, Graduate School of Medicine, Yamaguchi University, Ube 755-8505, Japan, 3.Department of Genetics, Saitama Children’s Medical Center, Saitama 330-8777, Japan, 4.Department of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551, Japan, 5.Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-0046, Japan)