The Molecular Biology Society of Japan

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[2SP-02-05_2P-186] The promising chemical modifications in the siRNA seed region that can avoid off-target effects by steric hindrance or thermodynamic stability

Seongjin An1, Yoshiaki Kobayashi2, Kohei Nomura3, Yasuaki Kimura3, Hiroshi Abe3, Akase Dai4, Misako Aida5, Kumiko UiTei1,2 (1.Grad. Sch. of Frontier Sci., Univ. of Tokyo, 2.Grad. Sch. of Sci., Univ. of Tokyo, 3.Grad. Sch. of Sci., Nagoya Univ, 4.AIDI Center, Hiroshima Univ, 5.ORACC, Hiroshima Univ.)

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