10:42 AM - 10:57 AM

[3AS-10-05] Hypoxia-induced epigenetic changes coordinate transcription start site selection and translational control through remodeling of 5’UTRs

^○Kathleen Watt¹, Bianca Dauber², Predrag Jovanovic^3,4, Krzysztof Szkop¹, Laura Lee⁵, Shan Chen¹, Ranveer Palia^3,4, Ivan Topisirovic^3,4, Ola Larsson¹, LynneMarie Postovit^2,5 (1.Dept. of Onk-Pat, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden, 2.Dept. of Biomedical and Molecular Sciences, Queen’s Univ., Kingston, ON, Canada, 3.Lady Davis Institute, Sir Mortimer B. Davis Jewish General Hospital, Montréal, QC, Canada, 4.Gerald Bronfman Dept. of Oncology, Division of Experimental Medicine and Dept. of Biochemistry McGill Univ., Montréal, QC, Canada., 5.Dept. of Oncology, Univ. of Alberta, Edmonton, AB, Canada.)