[1P-872_1SP-11-15] Development of a novel co-culture system to mimic the characteristics of pancreatic ductal adenocarcinoma in vitro

^○Tatsuya Kometani^1,2, Koki Kamo^2,3, Keisuke Sekine² (1.Dept. Nutritional Science and Food Safety, Tokyo University of Agriculture, 2.Lab. of Cancer Cell Systems, National Cancer Center Research Institute, 3.Dept. Bioscience, Tokyo University of Agriculture)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-873] APCmin/RasV12-induced cancer cells invade into lymphatic vessels through Endothelial-to-Mesenchymal transition(EndMT)

^○HANCHENG LIN, Shunsuke Kon, Kazuki Nakai, Eilma Akter (Div. of Mol. Biol.,Div. of Cancer .Cell.Biol.,Res.Inst. for Biomed.Sci.,Tokyo Univ. of Sci)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-874_1SP-11-10] Targeted delivery of miR-143 and Doxorubicin to SW480 cells using a molecular hybrid of microRNA and aptamer

^○KHANITTHA LAOWICHUWAKONNUKUL¹, Boonchoy Soontornworajit², Pichayanoot Rotkrua¹ (1.Division of Biochemistry, Department of Preclinical Science, Faculty of Medicine, Thammasat University, Pathumthani 12120, Thailand, 2.Department of Chemistry, Faculty of Science and Technology, Thammasat University, Pathumthani, 12120, Thailand)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-875] Screening of small molecule compounds that inhibit interaction between PAK and Akt

^○Azumi Urata¹, Hiroaki Nagano², Keisuke Onishi³, Yukiko Gotoh², Maiko Higuchi¹ (1.Dept. of Life. Sci., Grad. Sch. of Sci. ,Rikkyo Univ., 2.Grad. Sch. of Pharm. Sci., Univ. of Tokyo, 3.Dept. of Chem. Biotech., Univ. of Tokyo)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-876_1SP-11-14] Inhibition of glutamate dehydrogenase, not glutaminase shows high efficacy to NSCLC cells that exhibit tolerance to Osimertinib.

^○Taichi Oshima, Kenta Furuichi, Kousei Ito, Shigeki Aoki (Lab. of Biopharm., Grad. Sch. of Pharm. Sci., Chiba Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-877] Angiogenesis and elevation of αSMA expression in pericytes inside on-chip tumor model using translocation renal cell carcinoma

^○Atsuya Kitada¹, Hang Zhou¹, Kazuya Fujimoto¹, Miwa Tanaka², Masaya Baba³, Takuro Nakamura⁴, Ryuji Yokokawa¹ (1.Dept. of Micro Eng., Grad. Sch. of Eng., Kyoto Univ., 2.The Cancer Institute, JFCR, 3.IRCMS, Kumamoto Univ., 4.IMS, Tokyo Medical Univ.)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-878_1SP-11-07] Development of a novel nucleic acid drug for the treatment of head and neck squamous cell carcinoma

^○Momoka Ono¹, Yuki Yamamoto^2,1, Yu Iwai², Manami Takeda^2,1, Ryouu Takahashi^2,1, Hidetoshi Tahara^1,2 (1.Dept. of Cell & Mol. Biol., Sch. of Pharm. Sci., Univ. of Hiroshima, 2.Dept. of Cell & Mol. Biol., Grad. Sch. of Biomed. & Health. Sci., Univ. of Hiroshima)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-879] Suicide gene therapy using retroviral replicating vectors for human ovarian cancer

^○Nao Ogawa^1,2, Lisa Isoda², Emiko SonodaFukuda², Yuya Takeuchi^1,2, Toru Takarada³, Kosei Hasegawa⁴, Noriyuki Kasahara⁵, Shuji Kubo² (1.Dept. of Biomed. Chem., Grad. Sch. of Sci. & Tech., Kwansei Gakuin Univ., 2.Lab. of Mol. & Genetic Therap., Advanced Med. Sci., Hyogo Med. Univ., 3.Lab. of Functional Mol. Chem., Kobe Pharm. Univ., 4.Dept. of Gynecologic Oncology, Saitama Med. Univ. International Med. Ctr., 5.Dept. of Neuro. Surg. & Rad. Oncology, UCSF)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-880_1SP-11-13] Hypoxic stress decreases CD38 expression via up-regulation of microRNA-26 in multiple myeloma

^○Sayaka Iwama¹, Akihiro Kitadate², Yuto Takahashi¹, Wataru Kuroki², Masahiro Yamada², Naoto Takahashi² (1.Dept. of Life Sci., Grad. Sch. of Eng. Sci., Univ. of Akita, 2.Dept. of Hematology, Nephrology, and Rheumatology, Grad. Sch. of Med., Univ. of Akita)

The 46th Annual Meeting of the Molecular Biology Society of Japan

[1P-881] Anti-tumor effects of antimicrobial peptides, Drosocin and Cecropin A against hematopoietic tumors in Drosophila mxc mutant larvae

^○Marina Hirata, Yoshihiro Inoue (Biomedical Res. Ctr., Kyoto Inst. Tech.)

The 46th Annual Meeting of the Molecular Biology Society of Japan