11:40 〜 11:50

[2T05m-04] PARP1 inhibitors alleviate injury in ARH3-deficient mice and human cells

^○青山和正¹, 間下雅士¹, Bu Xiangning¹, 加藤治郎¹, 石渡-遠藤広子¹, Stevens Linda A¹, 笠松厚志¹, Wolfe Lynne A², Toro Camilo², Adams David^2,3, Markello Thomas², Gahl William A^2,3, Moss Joel¹ (1.Pulmonary Branch, National Heart, Lung, and Blood Institute, National Institutes of Health (NIH), 2.NIH Undiagnosed Diseases Program, Common Fund, Office of the Director, National Institutes of Health (NIH), 3.Office of the Clinical Director, National Human Genome Research Institute, National Institutes of Health (NIH))

キーテクノロジー：DNA sequence

ARH3、Poly(ADP-ribosyl)ation、Parthanatos