11:05 〜 11:25

[2AW-19-7] Translational switch during integrated stress response (ISR) provides oncogenic capability to tumor suppressor p53

Maria Jose Iniesta Lopez^1,3、Rafaela Lacerda²、Bruna Filipa Pereira²、Masatoshi Hagiwara³、Luisa Romao²、Michiyuki Matsuda⁴、〇Marco M Candeias^1,2 (1.Molecular and RNA Cancer Unit, Graduate school of Medicine, Kyoto University、2.Department of Human Genetics, National Institute of Health Doutor Ricardo Jorge, Lisbon, Portugal、3.Department of Anatomy and Developmental Biology Graduate School of Medicine, Kyoto University、4.Laboratory of Bioimaging and Cell Signaling, Graduate School of Biostudies, Kyoto University)

p53、mRNA translation、stress response、cancer mutation