[1L10-14] Radiation Chemistry, Biology and Gamma-ray Application

[1L12] Influence of secondary electrons on dissociation of biomolecules in liquids by fast heavy-ion collisions

*Hidetsugu Tsuchida¹, Kensei Kitagima¹, Shinji Nomura¹, Akihiro Kajiwara¹, Takuya Majima¹, Manabu Saito¹ (1. Kyoto Univ.)

Keywords:Biomolecules, Radiation damage, liquids, Secondary electrons, Fast heavy-ions

The effect of liquid environment on fast heavy-ion radiation damage of biomolecules was studied to understand DNA damage by ionizing radiation at the atomic level. Biomolecules targets used were glycine and proline. Microjets of biomolecular aqueous solutions under vacuum were irradiated by fast heavy ions. Reaction products were analyzed by time-of-flight secondary ion mass spectrometry. We investigated LET (linear energy transfer) dependence of the degree of molecular dissociation, and discussed influence of secondary electrons originating from ionized water molecules on damage of biomolecules in liquid environments.