2021 Annual Meeting

Presentation information

Oral presentation

VII. Health Physics and Environmental Science » Health Physics and Environmental Science

[2M04-08] Dose Evaluation

Thu. Mar 18, 2021 3:45 PM - 5:15 PM Room M (Zoom room 13)

Chair: Takeyoshi Sunagawa (Fukui Univ. of Tech.)

4:00 PM - 4:15 PM

[2M05] Study of Local Heating in Combination Treatment of Hyperthermia with Radiation Therapy for Breast Cancer Treatment

*Edmond Chen1, Aditya Rakhmadi2, Kazuyuki Saito2, Youichiro Wada1, Mitsuru Uesaka1 (1. UTokyo, 2. Chiba Univ.)

Keywords:Hyperthermia, Radiation Therapy, Microwave Antenna, Gene analysis, Breast Cancer

By increasing the temperature in the tissue, hyperthermia treatment aims to make the cells more sensitive and eventually kill the targeted tissues. The combination of hyperthermia with radiation-based treatment has shown an increase in the damages inflicted to the tumor cells. To study this sensitization mechanism, local application of the combination therapy was made experimentally as it would be in the patient body. By reproducing this local treatment, the purpose is to analyze the potential differences obtained depending on the applied therapy. These results give a better understanding of the biological mechanisms involved and unveil possible optimizations in the combination treatment in order to reach higher efficiency in killing the tumor.