[Symposium 5] Host-Pathogen interaction (4)

[S5-5] A sex biased imbalance of T-follicular regulatory (Tfr) cells, T-peripheral helper (Tph) cells and extrafollicular B-cells correlates with antibody responses in COVID-19 patients

Jonas Norskov Sondergaard¹, Janyerkye Tulyeu¹, Ryuya Edahiro^2,3, Yuya Shirai^2,3, Yuta Yamaguchi^2,4, Teruaki Murakami^2,4, Takayoshi Morita^2,4, Yasuhiro Kato^2,4, Haruhiko Hirata², Yoshito Takeda², Daisuke Okuzaki^5,6,9,10, Shimon Sakaguchi^7,8, Atsushi Kumanogoh^2,4,9,10, Yukinori Okada^{3,9,10,11,12,13}, ^○James Badger Wing^1,14 (1.Human Single Cell Immunology Team, CiDER, Osaka University, 2.Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan, 3.Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan., 4.Department of Immunopathology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan., 5.Laboratory of Human Immunology (Single Cell Genomics), WPI-IFReC, Osaka University, Suita, Japan., 6.Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Japan, 7.Laboratory of Experimental Immunology, WPI-IFReC, Osaka University, Suita, Japan., 8.Department of Experimental Pathology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan., 9.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI), Osaka University, Suita, Japan., 10.CiDER, Osaka University, Suita, Japan., 11.Laboratory of Statistical Immunology. WPI-IFReC, Osaka University, Suita, Japan., 12.Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Suita, Japan., 13.Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., 14.Human Immunology (single cell immunology), WPI-IFReC, Osaka University)