[P1-4-1] [Poster Tour]Somapacitan, a once-weekly reversible albumin-binding growth hormone (GH) derivative, is well tolerated and convenient in adults with GH deficiency (AGHD): results from a 26-week randomised, controlled phase 3 trial

Gudmundur Johannsson¹, Ulla Feldt-Rasmussen², Ida Holme Håkonsson³, Henrik Biering⁴, Patrice Rodien⁵, Shigeyuki Tahara⁶, Toogood Andrew⁷, ^○Michael Højby Rasmussen³ (1.Department of Internal Medicine, University of Gothenburg, 2.Medical Endocrinology, Rigshospitalet, Copenhagen University Hospital, 3.Global Development, Novo Nordisk A/S, 4.MediCover Berlin-Mitte MVZ, 5.D?partement d'endocrinologie-diab?tologie-nutrition, CHU Angers Centre Hospitalier Universitaire, 6.Department of Neurosurgery, Nippon Medical School, 7.Department of Endocrinology, Queen Elizabeth Hospitals Birmingham)

[P1-4-2] Incidences of Type 2 Diabetes Mellitus and Neoplasm in Growth Hormone Treated Children in Japan

^○Susumu Yokoya¹, Tomonobu Hasegawa², Keiichi Ozono³, Hiroyuki Tanaka⁴, Susumu Kanzaki⁵, Toshiaki Tanaka⁶, Kazuo Chihara⁷, Nan Jia⁸, Christopher Child⁹, Noriyuki Iwamoto¹⁰, Yoshiki Seino¹¹ (1.Department of Medical Subspecialties, National Center for Child Health and Development, 2.Department of Pediatrics, Keio University School of Medicine, 3.Department of Pediatrics, Osaka University Graduate School of Medicine / Faculty of Medicine, 4.Department of Pediatrics, Okayama Saiseikai General Hospital, 5.Department of Pediatrics, Tottori University Faculty of Medicine, 6.Tanaka Growth Clinic, 7.Department of Internal Medicine, Hyogo Prefectural Kakogawa Medical Center, 8.Lilly Research Laboratiries, Eli Lilly and Company, USA, 9.Lilly Research Laboratiries, Eli Lilly and Company, UK, 10.Medical Science, Eli Lilly Japan K.K., 11.JCHO Osaka Hospital)

[P1-4-3] Sequence variations in genes of the GH-IGF-1 axis in children with idiopathic short stature

^○Atsushi Hattori¹, Yuko Katoh-Fukui¹, Keiko Matsubara¹, Maki Igarashi¹, Erina Suzuki¹, Akie Nakamura¹, Hiroyuki Tanaka², Keisuke Nagasaki³, Koji Muroya⁴, Reiko Horikawa⁵, Shinobu Ida⁶, Toshiaki Tanaka⁷, Tsutomu Kamimaki⁸, Tsutomu Ogata⁹, Maki Fukami¹ (1.Department of Molecular Endocrinology, National Research Institute for Child Health and Development, 2.Department of Pediatrics, Okayama Saiseikai General Hospital, 3.Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, 4.Department of Endocrinology and Metabolism, Kanagawa Children’s Medical Center, 5.Division of Endocrinology and Metabolism, National Center for Child Health and Development, 6.Department of Gastroenterology and Endocrinology, Osaka Medical Center and Research institute for Maternal and Child Health, 7.Tanaka Growth Clinic, 8.Department of Pediatrics, Shizuoka City Shimizu Hospital, 9.Department of Pediatrics, Hamamatsu University School of Medicine)

[P1-4-4] Mouse Polycomb Cbx2 Functions in Skeletal Lineage

^○Yuko Katoh-Fukui¹, Miyuki Shindo², Rie Natsume³, Kenji Sakimura³, Hideki Tsumura², Maki Fukami¹ (1.Molecular Endocrinology, National Center for Child Health and Development, 2.Laboratory Animal Facility, National Center for Child Health and Development, 3.Department of Cellular Neurobiology, Brain Research Institute, Niigata University)

[P1-4-5] Practical growth charts for Japanese children with Noonan syndrome

^○Tsuyoshi Isojima^1,2, Satoru Sakazume³, Tomonobu Hasegawa⁴, Tsutomu Ogata⁵, Toshio Nakanishi⁶, Toshiro Nagai², Susumu Yokoya⁷ (1.Department of Pediatrics, Teikyo University School of Medicine, 2.Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, 3.Department of Pediatrics, Dokkyo Medical University Koshigaya Hospital, Koshigaya, 4.Department of Pediatrics, Keio University School of Medicine, 5.Department of Pediatrics, Hamamatsu University School of Medicine, 6.Department of Pediatric Cardiology, The Heart Institute, Tokyo Women’s Medical University, 7.Department of Medical Subspecialties, National Center for Child Health and Development)

[P1-4-6] ★[High Score]Infantile growth pattern of girls with Turner syndrome

^○Satsuki Nishigaki¹, Takashi Hamazaki¹, Akitoshi Tsuruhara², Toshiko Yoshida³, Takuji Imamura⁴, Hiroshi Inada⁵, Keinosuke Fujita¹, Haruo Shintaku¹ (1.Department of Pediatrics, Osaka City University Graduate School of Medicine, 2.Department of Pediatrics, Izumi municipal hospital, 3.Department of Pediatrics, Osaka Saiseikai Senri Hospital, 4.Department of Pediatrics, PL general hospital, 5.Osaka City Public Health Office)

[P1-4-7] ★[High Score]Safety and efficacy of daily rhGH treatment up to near adult height in Japanese short children born SGA: final report from a multi-center, open-label, long-term study

^○Toshiaki Tanaka¹, Susumu Yokoya², Yuko Hoshino³, Shintaro Hiro³, Nobuhiko Ohki³ (1.., Tanaka Growth Clinic, 2.National Center for Child Health and Development, 3.Pfizer Japan Inc.)

[P1-4-8] ★[High Score]Study of mRNA expression of Insulin/IGF axis in neonatal period

^○Masanobu Fujimoto¹, Yuki Kawashima Sonoyama¹, Aya Imamoto¹, Naoki Miyahara¹, Fumiko Miyahara¹, Rei Nishimura¹, Mazumi Miura¹, Keiichi Hanaki², Susumu Kanzaki¹ (1.Division of Pediatrics and Perinatology, Tottori University Faculty of Medicine, 2.Department of Women's and Children's Family Nursing, Tottori University Faculty of Medicine)

[P1-4-9] Adult height in Japanese Prader-Willi syndrome patients with growth hormone treatment

^○Yoriko Hatta^1,2, Takashi Kamijo³ (1.Department of Pediatrics, Japan Red Cross Nagoya Daiichi Hospital, 2.Iwayama Pediatric Clinic, 3.Nagoyaka Children's Clinic)

[P1-4-10] Idiopathic short stature children with free T4 in the low-normal range during the first year of therapy with recombinant human growth hormone needs attention

^○Wei Wang, Ling Shi, Zhi Cui (Pediatric Endocrinology Clinic,, Third Affiliated Hospital of Zhengzhou University)

[P1-4-11] Growth and glucose metabolism after allogenic bone marrow transplantation for thalassemia major

^○Wenqin Lao¹, Liyang Liang², Hui Ou², Zhe Meng², Lele Hou² (1.Department of Pediatrics, The Second Affiliated Hospital of Guangzhou Medical University, 2.Department of Pediatrics, Sun Yat-sen Memorial Hospital)

[P1-4-12] A case with duplication of 20qter and deletion of 20pter due to maternal pericentric inversion, presenting with Silver-Russell syndrome-like phenotypes.

^○Chie Takahashi¹, Akie Nakamura², Mayuko Tamura¹, Hiroyuki Tanaka¹, Tsuyoshi Isojima¹, Akira Oka¹, Masayo Kagami², Sachiko Kitanaka¹ (1.Department of Pediatrics, The University of Tokyo Hospital, 2.Department of Molecular Endocrinology, National Research Institute for Child Health and Development)

[P1-4-13] A Novel de novo Germline Mutation Glu40Lys in AKT3 causes Megalencephaly with Growth Hormone Deficiency.

^○Nagahara Keiko^1,2, Masaki Takagi^1,3, Takanari Fujii², Gen Nishimura⁴, Mitsuhiro Kato², Kazushige Dobashi², Kazuo Itabashi², Satoshi Narumi³, Tomonobu Hasegawa³ (1.Department of Endocrinology and Metabolism, Tokyo Metropolitan Children's Medical Center, 2.Department of Pediatrics, Showa University School of Medicine, 3.Department of Pediatrics, Keio University School of Medicine, 4.Department of Radiology, Tokyo Metropolitan Children's Medical Center)

[P1-4-14] Onset of puberty in extremely low birth weight children born small for gestational age and treated with GH

^○Shinsuke Onuma, Shinnosuke Tsuji, Mikiko Koizumi, Hiroyuki Yamada, Yasuko Shoji, Masanobu Kawai, Yuri Etani, Shinobu Ida (Department of Pediatric Gastroenterology, Nutrition and Endocrinology, Osaka Medical Center and Research Institute for Maternal and Child Health)

[P1-4-15] Nipbl deletion in pyramidal neurons results in postnatal growth retardation and early lethality

^○Xiaohui Wu, Chun Zou (Department of Endocrinology, Children’s Hospital of Zhejiang University School of Medicine)

[P1-4-16] A 3-year-old girl with 46,XX, upd(14)mat/47,XX,+14 mosaicism caused by postzygotic duplication of a maternally derived chromosome 14

^○Kikumi Ushijima^1,2, Syuichi Yatsuga¹, Akie Nakamura², Yasutoshi Koga¹, Maki Fukami², Masayo Kagami² (1.Department of Pediatrics and Child Health, Kurume University School of Medicine, 2.Department of Molecular Endocrinology, National Research Institute for Child Health and Development)

[P1-4-17] Acromicric Dysplasia Caused by a Novel Heterozygous Mutation of FBN1 and Experience of Growth Hormone Treatment

^○Su Jin Kim¹, Sunag Won Park², Young Bae Sohn³, Sung Yoon Cho⁴ (1.Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 2.Department of Pediatrics, Cheil General Hospital, Dankook University College of Medicine, 3.Department of Medical Genetics, Ajou University Hospital, 4.Department of Pediatrics, Myongji Hospital, Seonam University College of Medicine)

[P1-4-18] Effect of Growth Hormone Therapy on Height Velocity in Korean Children with Idiopathic Short Stature (ISS): a Randomised Controlled Trial

^○Woo Yeong Chung¹, Premila Paranchothy², Byung-Kyu Suh³ (1.Paediatrics Department, Inje University Busan Paik Hospital, 2.Asia Pacific Regional Medical Affairs, Merck Ltd, 3.Department of Pediatrics, The Catholic University of Korea)

[P1-4-19] Outcome of Growth Hormone Therapy on children with IDIOPATHIC GROWTH HORMONE DEFICIENCY : AN INDIAN EXPERIENCE

^○CECIL Khakha¹, Pragya Jain¹, Gordee Singh¹, AMIT JAGGI¹, Deepika Khakha² (1.DEPARTMENT OF PEDIATRICS, E.S.I. HOSPITAL , OKHLA INDUTRIAL AREA PHASE-1 , NEW DELHI-110020, 2.COLLEGE OF NURSING, ALL INDIA INSTITUTE OF MEDICAL SCIENCES , NEW DELHI)

[P1-4-20] GnRH agonist treatment for central precocious puberty can improve the final adult height in Chinese girls

^○Ying Yanqin, Hou Ling, Liang Yan, Xaoping Luo (pediatric department, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology)

[P1-4-21] COMPARISON OF GROWTH IN CHILDREN FROM RURAL PUNE, INDIA, ON VARIOUS GROWTH REFERENCES

Priya Gupta, ^○Rahul Jahagirdar, Vaman Khadilkar, Ruma Deshpande, Sanjay Lalwani (Department of Pediatric Endocrinology, Bharati Vidyapeeth University Medical College Pune ,India)

[P1-4-22] A secular trend of ages at menarche and spermarche in Korean adolescents over a decade: using the Korea Youth Risk Behavior Web-based Survey (KYRBS) 2006-2015.

Eun Mi Jung¹, Eun Hee Ha¹, ^○Hae Kim² (1.Department of Preventive Medicine, School of Medicine, Ewha Womans University, 2.Department of Pediatrics, School of Medicine, Ewha Womans University)

[P1-4-23] NUTRITIONAL STATUS AND ANAEMIA AMONG PRIMARY SCHOOL CHILDREN IN MYMENSINGH DISTRICT .

^○Mohammad Mahmudul (DEPARENT OF PAEDIATRICS, MYMENSINGH MEDICAL COLLEGE)

[P1-4-24] Efficacy and safety of recombinant human growth hormone treatment in six Chinese patients with Noonan syndrome

^○Zhi-Hui Liu, Shi-yao Wang, Hui Pan, Hong-Bo Yang, Lin-jie Wang, Feng-Ying Gong, Zi-meng Jin, Hui-juan Zhu (Department of Endocrinology, Key Laboratory of Endocrinology of Ministry of Health,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College)

[P1-4-25] Enzyme replacement therapy ameliorated growth impairment of Mucopolysaccharidosistype II patients

^○Yusuke Hamada, Touko Shibuya, Kenichi Yamamoto, Hidehito Kondo, Kaori Irahara, Takanobu Otomo, Norio Sakai, Keiichi Ozono (Department of Pediatrics, Graduate school of medicine, Osaka University)

Session information

P1-4: Growth