[AsCNP_P10] Poster Session 10
Depression 4

Fri. Oct 11, 2019 1:40 PM - 3:10 PM Poster Hall (Multi-purpose Hall)

Chair: ‌Hirokazu MIZOGUCHI (Department of Psysiology and Anatomy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, Japan)

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1:40 PM - 1:45 PM

[AsCNP-P10-1] Possible involvement of histone acetylation in the stress responses associated with central 5-HT neuronal regulation in mice

^○Kazuya MIYAGAWA, Atsumi MOCHIDA-SAITO, Kazuhiro KUROKAWA, Hidenao KIMIJIMA, Minoru TSUJI, Hiroshi TAKEDA (Departmnent of Pharmacology, School of Pharmacy, International University of Health and Welfare, Tochigi, Japan)

1:45 PM - 1:50 PM

[AsCNP-P10-2] BDNF/VEGF release and mTORC1 activation in the medial prefrontal cortex are required for the antidepressant actions of resolvin E1 in lipopolysaccharide-induced depression model mice

^○Satoshi DEYAMA¹, Kohei ISHIMURA², Hayato FUKUDA^{2, 3}, Satoshi SHUTO², Masabumi MINAMI⁴, Katsuyuki KANEDA¹ (1. Lab. of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, 2. Lab. of Organic Chemistry for Drug Development, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan, 3. Pharmaceutical Organic Chemistry Lab., Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, 4. Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan)

1:50 PM - 1:55 PM

[AsCNP-P10-3] The glutamate release inhibition from presynaptic site in mice medial prefrontal cortex via a delta opioid receptor

^○Akiyoshi SAITOH¹, Daisuke YAMADA¹, Jun-Ichiro OKA¹, Hiroshi NAGASE² (1. Lab Pharmacol, Fac Pharm Sci, Tokyo Univ of Science, Chiba, Japan, 2. IIIS, University of Tsukuba, Ibaraki, Japan )

1:55 PM - 2:00 PM

[AsCNP-P10-4] Repeated social defeat stress induces microglial activation and myelin abnormality in the corpus callosum: a potential link to depression-like behavior

^○Tsubasa IIDA¹, Kazuo KUNISAWA¹, Sei SAITOH², Aika KOSUGE¹, Wulaer BOLATI^{3, 4}, Willy Jaya SUENTO^{4, 5}, Yasuko YAMAMOTO⁴, Akihiro MOURI¹, Kuniaki SAITO^{3, 4}, Toshitaka NABESHIMA³ (1. Department of Regulatory Science for Evaluation & Development of Pharmaceuticals & Devices, Fujita Health University Graduate School of Health Sciences, Aichi, Japan, 2. Department of Anatomy II and Cell Biology, Fujita Health University School of Medicine, Aichi, Japan., 3. Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science, Aichi, Japan, 4. Department of Disease Control and Prevention, Fujita Health University Graduate School of Health Sciences, Aichi, Japan, 5. Department of Psychiatry, Hasanuddin University, South Sulawesi, Indonesia)

2:00 PM - 2:05 PM

[AsCNP-P10-5] Repeated social defeat stress induces depression-like behavior through the decrease of GLT-1 ubiquitination in the prefrontal cortex of mice

^○Aika KOSUGE¹, Kazuo KUNISAWA¹, Tsubasa IIDA¹, Wulaer BOLATI^{2, 3}, Willy Jaya SUENTO^{3, 4}, Yasuko YAMAMOTO³, Akihiro MOURI¹, Kuniaki SAITO^{2, 3}, Toshitaka NABESHIMA² (1. Department of Regulatory Science for Evaluation & Development of Pharmaceuticals & Devices, Fujita Health University Graduate School of Health Sciences, Aichi, Japan, 2. Advanced Diagnostic System Research Laboratory, Fujita Health University Graduate School of Health Science, Aichi, Japan, 3. Department of Disease Control and Prevention, Fujita Health University Graduate School of Health Sciences, Aichi, Japan, 4. Department of Psychiatry, Hasanuddin University, South Sulawesi, Indonesia.)

2:05 PM - 2:10 PM

[AsCNP-P10-6] Activation of 5-HT_1A receptor protects the myelin loss in a mouse model of stress-maladaptation

^○Kazuhiro KUROKAWA, Minoru TSUJI, Kazuya MIYAGAWA, Atsumi MOCHIDA-SAITO, Hiroshi TAKEDA (Department of Pharmacology, School of Pharmacy, International University of Health and Welfare, Tochigi, Japan)

2:10 PM - 2:15 PM

[AsCNP-P10-7] Dysfunction of protein kinase C-beta I (PKCβI) - serotonin transporter (SERT) systems is involved in depression-like behaviors in stressed mice

^○Takahiro ITO¹, Yuka HIRAMATSU¹, Mizuki UCHIDA¹, Akira YOSHIMI¹, Norio OZAKI², Yukihiro NODA^{1, 2} (1. Division of Clinical Sciences and Neuropsychopharmacology, Meijo University Faculty and Graduate School of Pharmacy, Nagoya, Japan, 2. Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan)